The Kimchi Lab is committed to determining the causes and treatments of delirium through a combination of translational and clinical research.
Delirium is an acute and fluctuating disturbance of attention and awareness. This dramatic disorder is most common in elderly patients and patients with neurologic diseases such as dementia. Delirium can be associated with complications such as falls and can suggest a person is at higher risk of dependence and death.
At any given time, approximately 20% of patients in hospital wards suffer from delirium. Though some epidemiology studies have identified key risk factors for delirium, including aging, sedation, and inflammation, this data has failed to translate into satisfactory therapies. Despite its profound and alarming nature, delirium remains poorly understood and difficult to treat due an incomplete understanding of its pathophysiology.